Abbreviation: | AT |
Aliases: | ATIII, AT3 |
Gene Symbol: | SERPINC1 |
SubUnit: |
Type: | serpin |
Main Action: | Inhibits thrombin, FIX, FX, FXI |
Genomic Reference Sequence: | NG_012462.1 |
Locus Reference Genomic (LRG): | LRG_577 |
LOVD: | http://www.LOVD.nl/SERPINC1 |
Locus Specific Database (LSDB): | |
Amino Acid Numbering Conversion Factor (Old > New;+/-): | 32 |
Variant Details: Antithrombin (1)
Predicted Mr (da): | 52,602 |
Predicted pl: | 6 |
Gene Size (bp): | 13,528 |
Transcript Size (nt): | 1,552 |
Number of Exons: | 7 |
Gene Location: | 1q23-q25.1 |
Number of Amino Acids: | 464 |
Mature Protein: | 33-464 |
Observer Mr of Monomer (kDa): | 58 |
Plasma Concentration (ug/ml): | 140 |
Plasma Molarity (nM): | 2400 |
Half-life (h): | 5 |
cDNA Reference Sequence (NM): | NM_000488.3 |
Protein Reference Sequence (NP): | NP_000479.1 |
Reference cDNA Sequence +1ATG (fasta format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000488.fasta |
Reference cDNA Sequence +1ATG (GenBank format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000488.gb |
Reference cDNA Sequence +1ATG with translation and exons marked (pdf format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000488_SERPINC1.pdf |