| Abbreviation: | FVIII |
| Aliases: | Antihaemophilic factor, AHF, HEMA |
| Gene Symbol: | F8 |
| SubUnit: |
| Type: | membrane-bound cofactor |
| Main Action: | Cofactor for FIXa in the tenase complex |
| Genomic Reference Sequence: | NG_011403.2 |
| Locus Reference Genomic (LRG): | LRG_555 |
| LOVD: | https://databases.lovd.nl/shared/genes/F8 |
| Locus Specific Database (LSDB): | https://f8-db.eahad.org/ |
| Amino Acid Numbering Conversion Factor (Old > New;+/-): | 19 |
Variant Details: Factor VIII (1)
| Predicted Mr (da): | 267,009 |
| Predicted pl: | 7 |
| Gene Size (bp): | 186,932 |
| Transcript Size (nt): | 9,032 |
| Number of Exons: | 26 |
| Gene Location: | Xq28 |
| Number of Amino Acids: | 2,351 |
| Mature Protein: | 20-2351 |
| Observer Mr of Monomer (kDa): | 330 |
| Plasma Concentration (ug/ml): | 0.1 |
| Plasma Molarity (nM): | 0.3 |
| Half-life (h): | 10 |
| cDNA Reference Sequence (NM): | NM_000132.4 |
| Protein Reference Sequence (NP): | NP_000123.1 |
| Reference cDNA Sequence +1ATG (fasta format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000132.fasta |
| Reference cDNA Sequence +1ATG (GenBank format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000132.gb |
| Reference cDNA Sequence +1ATG with translation and exons marked (pdf format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000132_F8.pdf |