| Abbreviation: | FXI |
| Aliases: | Plasma thromboplastin antecedent |
| Gene Symbol: | F11 |
| SubUnit: |
| Type: | serine protease |
| Main Action: | Activates FIX |
| Genomic Reference Sequence: | NG_008051.1 |
| Locus Reference Genomic (LRG): | LRG_583 |
| LOVD: | https://databases.lovd.nl/shared/genes/F11 |
| Locus Specific Database (LSDB): | https://dbs.eahad.org/ |
| Amino Acid Numbering Conversion Factor (Old > New;+/-): | 18 |
Variant Details: Factor XI (1)
| Predicted Mr (da): | 70,109 |
| Predicted pl: | 8 |
| Gene Size (bp): | 23,718 |
| Transcript Size (nt): | 3,278 |
| Number of Exons: | 15 |
| Gene Location: | 4q35 |
| Number of Amino Acids: | 625 |
| Mature Protein: | 19-625 |
| Observer Mr of Monomer (kDa): | 80* |
| Plasma Concentration (ug/ml): | 5 |
| Plasma Molarity (nM): | 30 |
| Half-life (h): | 45 |
| cDNA Reference Sequence (NM): | NM_000128.3 |
| Protein Reference Sequence (NP): | NP_000119.1 |
| Reference cDNA Sequence +1ATG (fasta format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000128.fasta |
| Reference cDNA Sequence +1ATG (GenBank format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000128.gb |
| Reference cDNA Sequence +1ATG with translation and exons marked (pdf format): | https://coagbase.org/wp-content/uploads/2022/01/NM_0001284_F11.pdf |
*Factor XI circulates as a 160kDa homodimer of two 80kDa monomers