Abbreviation: | FXIII |
Aliases: | Fibrin stabilizing factor |
Gene Symbol: | F13A1 |
SubUnit: | A |
Type: | transglutaminase |
Main Action: | Crosslinks fibrin |
Genomic Reference Sequence: | NG_008107.1 |
Locus Reference Genomic (LRG): | LRG_549 |
LOVD: | https://www.LOVD.nl/F13A1 |
Locus Specific Database (LSDB): | https://dbs.eahad.org/ |
Amino Acid Numbering Conversion Factor (Old > New;+/-): |
Variant Details: Factor XIII** (A chain) (1)
Predicted Mr (da): | 83,268 |
Predicted pl: | 6 |
Gene Size (bp): | 176,614 |
Transcript Size (nt): | 3,863 |
Number of Exons: | 15 |
Gene Location: | 6p25.3-p24.3 |
Number of Amino Acids: | 732 |
Mature Protein: | 39-732 |
Observer Mr of Monomer (kDa): | 75** |
Plasma Concentration (ug/ml): | 10 |
Plasma Molarity (nM): | 30 |
Half-life (h): | 200 |
cDNA Reference Sequence (NM): | NM_000129.3 |
Protein Reference Sequence (NP): | NP_000120.2 |
Reference cDNA Sequence +1ATG (fasta format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000129.fasta |
Reference cDNA Sequence +1ATG (GenBank format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000129.gb |
Reference cDNA Sequence +1ATG with translation and exons marked (pdf format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000129_F13A1.pdf |
**Factor XIII circulates as a 326kDa tetramer of two A2B2