Fibrinogen (γ chain)

Abbreviation:FGN
Aliases:FN
Gene Symbol:FGG
SubUnit:γ
Type:insoluble polymer precursor
Main Action:Mechanical stabilisation of clot
Genomic Reference Sequence:NG_008834.1
Locus Reference Genomic (LRG):LRG_585
LOVD:https://www.LOVD.nl/FGG
Locus Specific Database (LSDB):https://site.geht.org/base-de-donnees-fibrinogene/
Amino Acid Numbering Conversion Factor (Old > New;+/-):
Variant Details: Fibrinogen (γ chain) (1)
Predicted Mr (da):51,511
Predicted pl:5
Gene Size (bp):8,486
Transcript Size (nt):2,072
Number of Exons:9
Gene Location:4q28
Number of Amino Acids:453
Mature Protein:27-453
Observer Mr of Monomer (kDa):49***
Plasma Concentration (ug/ml):3000
Plasma Molarity (nM):9000
Half-life (h):90
cDNA Reference Sequence (NM):NM_021870.3
Protein Reference Sequence (NP):NP_068656.2
Reference cDNA Sequence +1ATG (fasta format):https://coagbase.org/wp-content/uploads/2022/01/NM_021870.fasta
Reference cDNA Sequence +1ATG (GenBank format):https://coagbase.org/wp-content/uploads/2022/01/NM_021870.gb
Reference cDNA Sequence +1ATG with translation and exons marked (pdf format):https://coagbase.org/wp-content/uploads/2022/01/NM_021870_FGG.pdf
Variant Details: Fibrinogen (γ chain) (2)
Predicted Mr (da):49,497
Predicted pl:6
Gene Size (bp):
Transcript Size (nt):1,565
Number of Exons:10
Gene Location:
Number of Amino Acids:437
Mature Protein:27-437
Observer Mr of Monomer (kDa):
Plasma Concentration (ug/ml):
Plasma Molarity (nM):
Half-life (h):
cDNA Reference Sequence (NM):NM_000509.6
Protein Reference Sequence (NP):NP_000500.2
Reference cDNA Sequence +1ATG (fasta format):https://coagbase.org/wp-content/uploads/2022/01/NM_000509.fasta
Reference cDNA Sequence +1ATG (GenBank format):https://coagbase.org/wp-content/uploads/2022/01/NM_000509.gb
Reference cDNA Sequence +1ATG with translation and exons marked (pdf format):https://coagbase.org/wp-content/uploads/2022/01/NM_000509_FGG.pdf
***Fibrinogen circulates as a 340kDa complex of two each of A-, B- and C-chains