| Abbreviation: | MTHFR |
| Aliases: | 5,10-methylenetetrahydrofolate reductase (NADPH) |
| Gene Symbol: | MTHFR |
| SubUnit: |
| Type: | 5,10-methylenetetrahydrofolate reductase |
| Main Action: | Breakdown of homocysteine |
| Genomic Reference Sequence: | NG_013351.1 |
| Locus Reference Genomic (LRG): | LRG_726 |
| LOVD: | https://databases.lovd.nl/shared/genes/MTHFR |
| Locus Specific Database (LSDB): | |
| Amino Acid Numbering Conversion Factor (Old > New;+/-): |
Variant Details: MTHFR (1)
| Predicted Mr (da): | 74,597 |
| Predicted pl: | 5 |
| Gene Size (bp): | 20,242 |
| Transcript Size (nt): | 7,108 |
| Number of Exons: | 12 |
| Gene Location: | 1p36.3 |
| Number of Amino Acids: | 656 |
| Mature Protein: | 656 |
| Observer Mr of Monomer (kDa): | 77 |
| Plasma Concentration (ug/ml): | NA |
| Plasma Molarity (nM): | NA |
| Half-life (h): | NA |
| cDNA Reference Sequence (NM): | NM_005957.4 |
| Protein Reference Sequence (NP): | NP_005948.3 |
| Reference cDNA Sequence +1ATG (fasta format): | https://coagbase.org/wp-content/uploads/2022/01/NM_005957.fasta |
| Reference cDNA Sequence +1ATG (GenBank format): | https://coagbase.org/wp-content/uploads/2022/01/NM_005957.gb |
| Reference cDNA Sequence +1ATG with translation and exons marked (pdf format): | https://coagbase.org/wp-content/uploads/2022/01/NM_005957_MTHFR.pdf |