Abbreviation: | PAI-1 |
Aliases: | PLANH1 |
Gene Symbol: | SERPINE1 |
SubUnit: |
Type: | serpin |
Main Action: | Inhibition of TPA and UPA |
Genomic Reference Sequence: | NG_013213.1 |
Locus Reference Genomic (LRG): | LRG_597 |
LOVD: | https://databases.lovd.nl/shared/genes/SERPINE1 |
Locus Specific Database (LSDB): | |
Amino Acid Numbering Conversion Factor (Old > New;+/-): |
Variant Details: Plasminogen activator inhibitor type 1 (1)
Predicted Mr (da): | 45,060 |
Predicted pl: | 7 |
Gene Size (bp): | 12,144 |
Transcript Size (nt): | 3,156 |
Number of Exons: | 9 |
Gene Location: | 7q22.1 |
Number of Amino Acids: | 402 |
Mature Protein: | 24-402 |
Observer Mr of Monomer (kDa): | 52 |
Plasma Concentration (ug/ml): | 10 |
Plasma Molarity (nM): | 200 |
Half-life (h): | 0.1 |
cDNA Reference Sequence (NM): | NM_000602.4 |
Protein Reference Sequence (NP): | NP_000593.1 |
Reference cDNA Sequence +1ATG (fasta format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000602.fasta |
Reference cDNA Sequence +1ATG (GenBank format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000602.gb |
Reference cDNA Sequence +1ATG with translation and exons marked (pdf format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000602_SERPINE1.pdf |