Abbreviation: | PK |
Aliases: | Fletcher factor; Plasma prekallikrein; kininogenin |
Gene Symbol: | KLKB1 |
SubUnit: |
Type: | serine protease |
Main Action: | Antiangiogenic, profibrinolytic |
Genomic Reference Sequence: | NG_012095.2 |
Locus Reference Genomic (LRG): | LRG_565 |
LOVD: | https://databases.lovd.nl/shared/genes/klkb1 |
Locus Specific Database (LSDB): | |
Amino Acid Numbering Conversion Factor (Old > New;+/-): |
Variant Details: Prekallikrein (1)
Predicted Mr (da): | 71,343 |
Predicted pl: | 9 |
Gene Size (bp): | 30,965 |
Transcript Size (nt): | 2,258 |
Number of Exons: | 15 |
Gene Location: | 4q35.2 |
Number of Amino Acids: | 638 |
Mature Protein: | 20-638 |
Observer Mr of Monomer (kDa): | 86 |
Plasma Concentration (ug/ml): | 50 |
Plasma Molarity (nM): | 580 |
Half-life (h): | |
cDNA Reference Sequence (NM): | NM_000892.5 |
Protein Reference Sequence (NP): | NP_000883.2 |
Reference cDNA Sequence +1ATG (fasta format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000892.fasta |
Reference cDNA Sequence +1ATG (GenBank format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000892.gb |
Reference cDNA Sequence +1ATG with translation and exons marked (pdf format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000892_KLKB1.pdf |