| Abbreviation: | PS |
| Aliases: | PROSP; protein S (alpha); PSA |
| Gene Symbol: | PROS1 |
| SubUnit: |
| Type: | membrane-bound cofactor |
| Main Action: | Inactivation of FVa and FVIIIa |
| Genomic Reference Sequence: | NG_009813.1 |
| Locus Reference Genomic (LRG): | LRG_572 |
| LOVD: | https://databases.lovd.nl/shared/genes/PROS1 |
| Locus Specific Database (LSDB): | https://www.isth.org/page/ProteinSDeficiency |
| Amino Acid Numbering Conversion Factor (Old > New;+/-): |
Variant Details: Protein S (1)
| Predicted Mr (da): | 75,123 |
| Predicted pl: | 5 |
| Gene Size (bp): | 100,846 |
| Transcript Size (nt): | 3,372 |
| Number of Exons: | 15 |
| Gene Location: | 3q11.1 |
| Number of Amino Acids: | 676 |
| Mature Protein: | 42-676 |
| Observer Mr of Monomer (kDa): | 69 |
| Plasma Concentration (ug/ml): | 10(free) |
| Plasma Molarity (nM): | 145 |
| Half-life (h): | 42.5 |
| cDNA Reference Sequence (NM): | NM_000313.3 |
| Protein Reference Sequence (NP): | NP_000304.2 |
| Reference cDNA Sequence +1ATG (fasta format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000313.fasta |
| Reference cDNA Sequence +1ATG (GenBank format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000313.gb |
| Reference cDNA Sequence +1ATG with translation and exons marked (pdf format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000313_PROS1.pdf |
Variant Details: Protein S (2)
| Predicted Mr (da): | |
| Predicted pl: | |
| Gene Size (bp): | |
| Transcript Size (nt): | 3,468 |
| Number of Exons: | 16 |
| Gene Location: | 3q11.1 |
| Number of Amino Acids: | 708 |
| Mature Protein: | 42-708 |
| Observer Mr of Monomer (kDa): | |
| Plasma Concentration (ug/ml): | |
| Plasma Molarity (nM): | |
| Half-life (h): | |
| cDNA Reference Sequence (NM): | NM_001314077.1 |
| Protein Reference Sequence (NP): | NP_001301006.1 |
| Reference cDNA Sequence +1ATG (fasta format): | https://coagbase.org/wp-content/uploads/2022/01/NM_001314077.fasta |
| Reference cDNA Sequence +1ATG (GenBank format): | https://coagbase.org/wp-content/uploads/2022/01/NM_001314077.gb |
| Reference cDNA Sequence +1ATG with translation and exons marked (pdf format): | https://coagbase.org/wp-content/uploads/2022/01/NM_001314077_PROS1.pdf |