| Abbreviation: | FII |
| Aliases: | PT |
| Gene Symbol: | F2 |
| SubUnit: |
| Type: | serine protease |
| Main Action: | Converts fibrinogen to fibrin, activates PC, FXI, TAFI |
| Genomic Reference Sequence: | NG_008953.1 |
| Locus Reference Genomic (LRG): | LRG_551 |
| LOVD: | https://databases.lovd.nl/shared/genes/f2 |
| Locus Specific Database (LSDB): | |
| Amino Acid Numbering Conversion Factor (Old > New;+/-): | 43 |
Variant Details: Prothrombin (1)
| Predicted Mr (da): | 70,037 |
| Predicted pl: | 6 |
| Gene Size (bp): | 20,294 |
| Transcript Size (nt): | 2,039 |
| Number of Exons: | 14 |
| Gene Location: | 11p11.2 |
| Number of Amino Acids: | 622 |
| Mature Protein: | 44-622 |
| Observer Mr of Monomer (kDa): | 72 |
| Plasma Concentration (ug/ml): | 90 |
| Plasma Molarity (nM): | 1400 |
| Half-life (h): | 65 |
| cDNA Reference Sequence (NM): | NM_000506.4 |
| Protein Reference Sequence (NP): | NP_000497.1 |
| Reference cDNA Sequence +1ATG (fasta format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000506.fasta |
| Reference cDNA Sequence +1ATG (GenBank format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000506.gb |
| Reference cDNA Sequence +1ATG with translation and exons marked (pdf format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000506_F2.pdf |