| Abbreviation: | UK |
| Aliases: | UPA; URK; plasminogen activator, urinary; proUK; scuPA |
| Gene Symbol: | PLAU |
| SubUnit: |
| Type: | serine protease |
| Main Action: | activator of plasminogen |
| Genomic Reference Sequence: | NG_011904.1 |
| Locus Reference Genomic (LRG): | LRG593 |
| LOVD: | https://databases.lovd.nl/shared/genes/plau |
| Locus Specific Database (LSDB): | |
| Amino Acid Numbering Conversion Factor (Old > New;+/-): |
Variant Details: Prourokinase (1)
| Predicted Mr (da): | 48,523 |
| Predicted pl: | 9 |
| Gene Size (bp): | 6,363 |
| Transcript Size (nt): | 2,378 |
| Number of Exons: | 11 |
| Gene Location: | 10q22.2 |
| Number of Amino Acids: | 431 |
| Mature Protein: | 21-431 |
| Observer Mr of Monomer (kDa): | 54 |
| Plasma Concentration (ug/ml): | 0.0015 |
| Plasma Molarity (nM): | 0.04 |
| Half-life (h): | 0.03 |
| cDNA Reference Sequence (NM): | NM_002658.3 |
| Protein Reference Sequence (NP): | NP_002649.1 |
| Reference cDNA Sequence +1ATG (fasta format): | https://coagbase.org/wp-content/uploads/2022/01/NM_002658.fasta |
| Reference cDNA Sequence +1ATG (GenBank format): | https://coagbase.org/wp-content/uploads/2022/01/NM_002658.gb |
| Reference cDNA Sequence +1ATG with translation and exons marked (pdf format): | https://coagbase.org/wp-content/uploads/2022/01/NM_002658_PLAU.pdf |
Variant Details: Prourokinase (2)
| Predicted Mr (da): | 46,925 |
| Predicted pl: | 9 |
| Gene Size (bp): | |
| Transcript Size (nt): | 2,663 |
| Number of Exons: | 10 |
| Gene Location: | 10q22.2 |
| Number of Amino Acids: | 414 |
| Mature Protein: | 21-414 |
| Observer Mr of Monomer (kDa): | |
| Plasma Concentration (ug/ml): | |
| Plasma Molarity (nM): | |
| Half-life (h): | |
| cDNA Reference Sequence (NM): | NM_001145031.1 |
| Protein Reference Sequence (NP): | NP_001138503.1 |
| Reference cDNA Sequence +1ATG (fasta format): | https://coagbase.org/wp-content/uploads/2022/01/NM_001145031.fasta |
| Reference cDNA Sequence +1ATG (GenBank format): | https://coagbase.org/wp-content/uploads/2022/01/NM_001145031.gb |
| Reference cDNA Sequence +1ATG with translation and exons marked (pdf format): | https://coagbase.org/wp-content/uploads/2022/01/NM_001145031_PLAU.pdf |