Abbreviation: | TFPI |
Aliases: | TFPI1; Extrinsic pathway inhibitor (EPI); Lipoprotein-associated coagulation inhibitor (LACI) |
Gene Symbol: | TFPI |
SubUnit: |
Type: | Kunitz-type inhibitor |
Main Action: | Inhibition of coagulation initiation complex |
Genomic Reference Sequence: | NG_029714.2 |
Locus Reference Genomic (LRG): | LRG_604 |
LOVD: | https://databases.lovd.nl/shared/genes/TFPI |
Locus Specific Database (LSDB): | |
Amino Acid Numbering Conversion Factor (Old > New;+/-): |
Variant Details: Tissue factor pathway inhibitor (1)
Predicted Mr (da): | 35,015 |
Predicted pl: | 9 |
Gene Size (bp): | 90,206 |
Transcript Size (nt): | 3,859 |
Number of Exons: | 8 |
Gene Location: | 2q32 |
Number of Amino Acids: | 304 |
Mature Protein: | 29-304 |
Observer Mr of Monomer (kDa): | 42 |
Plasma Concentration (ug/ml): | 0.08 |
Plasma Molarity (nM): | 2.5 |
Half-life (h): | 1.2 |
cDNA Reference Sequence (NM): | NM_006287.6 |
Protein Reference Sequence (NP): | NP_006278.1 |
Reference cDNA Sequence +1ATG (fasta format): | https://coagbase.org/wp-content/uploads/2022/01/NM_006287.fasta |
Reference cDNA Sequence +1ATG (GenBank format): | https://coagbase.org/wp-content/uploads/2022/01/NM_006287.gb |
Reference cDNA Sequence +1ATG with translation and exons marked (pdf format): | https://coagbase.org/wp-content/uploads/2022/01/NM_006287_TFPI.pdf |