| Abbreviation: | TPA |
| Aliases: | t-PA |
| Gene Symbol: | PLAT |
| SubUnit: |
| Type: | serine protease |
| Main Action: | activator of plasminogen |
| Genomic Reference Sequence: | NG_023264.1 |
| Locus Reference Genomic (LRG): | LRG_570 |
| LOVD: | https://databases.lovd.nl/shared/genes/plat |
| Locus Specific Database (LSDB): | |
| Amino Acid Numbering Conversion Factor (Old > New;+/-): |
Variant Details: Tissue plasminogen activator (1)
| Predicted Mr (da): | 62,917 |
| Predicted pl: | 8 |
| Gene Size (bp): | 32,848 |
| Transcript Size (nt): | 3,062 |
| Number of Exons: | 14 |
| Gene Location: | 8p11.21 |
| Number of Amino Acids: | 562 |
| Mature Protein: | 36-562 |
| Observer Mr of Monomer (kDa): | 69 |
| Plasma Concentration (ug/ml): | 0.005 |
| Plasma Molarity (nM): | 0.07 |
| Half-life (h): | 0.03 |
| cDNA Reference Sequence (NM): | NM_000930.3 |
| Protein Reference Sequence (NP): | NP_000921.1 |
| Reference cDNA Sequence +1ATG (fasta format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000930.fasta |
| Reference cDNA Sequence +1ATG (GenBank format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000930.gb |
| Reference cDNA Sequence +1ATG with translation and exons marked (pdf format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000930_PLAT.pdf |