Abbreviation: | TPA |
Aliases: | t-PA |
Gene Symbol: | PLAT |
SubUnit: |
Type: | serine protease |
Main Action: | activator of plasminogen |
Genomic Reference Sequence: | NG_023264.1 |
Locus Reference Genomic (LRG): | LRG_570 |
LOVD: | https://databases.lovd.nl/shared/genes/plat |
Locus Specific Database (LSDB): | |
Amino Acid Numbering Conversion Factor (Old > New;+/-): |
Variant Details: Tissue plasminogen activator (1)
Predicted Mr (da): | 62,917 |
Predicted pl: | 8 |
Gene Size (bp): | 32,848 |
Transcript Size (nt): | 3,062 |
Number of Exons: | 14 |
Gene Location: | 8p11.21 |
Number of Amino Acids: | 562 |
Mature Protein: | 36-562 |
Observer Mr of Monomer (kDa): | 69 |
Plasma Concentration (ug/ml): | 0.005 |
Plasma Molarity (nM): | 0.07 |
Half-life (h): | 0.03 |
cDNA Reference Sequence (NM): | NM_000930.3 |
Protein Reference Sequence (NP): | NP_000921.1 |
Reference cDNA Sequence +1ATG (fasta format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000930.fasta |
Reference cDNA Sequence +1ATG (GenBank format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000930.gb |
Reference cDNA Sequence +1ATG with translation and exons marked (pdf format): | https://coagbase.org/wp-content/uploads/2022/01/NM_000930_PLAT.pdf |